NGS DNA Library Construction from Samples with Limiting Amounts of Degraded DNA

The Accel-NGS 1S DNA Library Kits enable users to make libraries from the impossible. Libraries can be made from damaged and degraded samples by using Swift's Adaptase™ technology. Unlike other library methods, the Adaptase technology can generate library molecules from single-stranded DNA fragments, which allow researchers to recover more of their input DNA from difficult samples compared to other commercially-available products.

The Accel-NGS 1S Library Kits will yield libraries in 2 hours from as little as 10 pg of input and fragments as short as 40 bp. The kits work with difficult-to-use samples, such as single-stranded DNA, heat-denatured pathogenic samples (microbial DNA), viral DNA, first-strand cDNA, ancient DNA, ChIP-Seq, and degraded DNA from FFPE samples. Accel-NGS 1S Library Kits are the best choice for users needing to sequence difficult-to-process samples, which cannot be sequenced by other methods. Expand your research by processing damaged and degraded samples on either the Illumina® or Ion Torrent™ NGS platforms.